Background: IRBs depend on diverse members with varying backgrounds to make complex ethical decisions. Yet, training practices for members are highly variable. Institutions require completion of CITI modules, onboarding by IRB Staff, however, few evaluate how well efforts translate into consistency and accuracy in identifying risk levels and applying ethical principles.
Program
Description: A centralized portal for IRB members to access training materials and info-packs was utilized after a survey conducted in 2021, where members had cited that accessibility to training materials was a challenge. Hence, we found a one-stop platform where members could access training materials and info-packs. Two local IRBs in Singapore (National Healthcare Group Domain Specific Review Board and SingHealth Centralised Institutional Review Board) had also collaborated to co-develop topic-specific e-Learn training modules for our IRB members through an interactive format. The online training modules were developed specifically to improve member competency, and consistency in reviewing human subjects’ research. Each module was 20 minutes long and addresses key topics e.g. Review of Remote Consent and Waiver of Consent. These modules included real protocol examples, decision-tree tools, and interactive quizzes. This project educates and assesses the effectiveness of our enhanced IRB members training program by assessing post-training feedback data from members.
Program
Assessment: The survey from IRB members after the launch of the initial 2 e-Learn training modules revealed that the understanding across domain increased and they showed improved confidence, especially in remote consent processes. Most of them also preferred the modular online learning over in-person or static slide decks. We are expecting to launch another 2 e-Learn training modules in July 2025 and will conduct another round of survey to evaluate its impact. The enhanced training program appeared to improve both confidence and consistency in IRB review. However, there may be no way to measure real-world impact on protocol review quality unless there’s an audit of actual IRB decisions before and after training.
Limitations: There could be some limitation to this since IRB members differ widely in expertise and experience. Hence, a one-size-fits-all training may have differential impact for some groups than others. Moreover, IRB members often have varying levels of participation (some may drop out or skip optional parts), reducing the consistency of data. There is also limited scope of evaluation as it may focus on knowledge retention or confidence but not long-term behavioural change.
Discussion: The project also highlighted the importance of using realistic protocol scenarios, not just theoretical content. Investing in structured online training for IRB members can enhance review quality, efficiency, and member satisfaction. This project demonstrates a scalable, adaptable model for IRB member education that institutions can tailor to evolving ethical and regulatory challenges. Although training had improved baseline readiness for our IRB members, certain areas (e.g., exemption categories, vulnerable populations) remained weak spots. We can also consider integration into the IRB online system (which members use for their reviews), to better track and assess the effectiveness of the training.
